Biophysics

Flexible instruments for interdisciplinary research

Biophysics is a highly diverse field of research. For example, the light microscopic investigation of biomaterials, proteins, and nucleic acids are hot topics in biophysics, to name a few. For these experiments, very precise and accurate instruments are required.

Abberior offers several microscope features which facilitate biophysics research at several levels of resolution:

• MINFLUX imaging mode for resolutions down to 2 nm

• MINFLUX single particle tracking with up to 10 kHz, i.e., 1 data point every 100 µs

• Adaptive Illumination for super-resolution STED imaging at minimal light dosages

• Lifetime imaging and advanced time-gating

• Pulsed high-power STED lasers for best resolutions with 2D and 3D super-resolution nanoscopy

• Detectors with superior detection efficiency (up to 65%)

• FLIM, PLIM

• Customization of the instrument’s hard- and software

Year	Journal	Author	Title
2013	Doctoral dissertation, Harvard University.	Kevin T Takasaki	Development and Application of Two-Photon Excitation Stimulated Emission Depletion Microscopy for Superresolution Fluorescence Imaging in Thick Tissue
2014	Progress In Electromagnetics Research	Frederik Gorlitz et al.	A STED Microscope Designed for Routine Biomedical Applications
2016	Turun yliopisto University of Turku	Sami Koho	BIOIMAGE INFORMATICS IN STED SUPER-RESOLUTION MICROSCOPY
2018	Journal of Biosciences	C ROOBALA et al.	Applications of STED fuorescence nanoscopy in unravelling nanoscale structure and dynamics of biological systems
2020	Biophysical Journal	Aurélien Barbotin et al.	Z-STED Imaging and Spectroscopy to Investigate Nanoscale Membrane Structure and Dynamics